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Effects of taurine supplementation following eccentric exercise in young adults

Publication: Applied Physiology, Nutrition, and Metabolism
25 June 2013

Abstract

The purpose of the present study was to investigate the effects of taurine supplementation on muscle performance, oxidative stress, and inflammation response after eccentric exercise (EE) in males. Twenty-one participants (mean age, 21 ± 6 years; weight, 78.2 ± 5 kg; height, 176 ± 7 cm) were selected and randomly divided into two groups: placebo (n = 10) and taurine (n = 11). Fourteen days after starting supplementation, subjects performed EE (3 sets until exhaustion, with EE of the elbow flexors on the Scott bench, 80% 1 repetition maximum (RM)). Blood samples were collected and muscle performance was measured on days 1, 14, 16, 18, and 21 after starting the supplements. Then, performance, muscle damage, oxidative stress, and inflammatory markers were analyzed. The taurine supplementation resulted in increased strength levels and thiol total content and decreased muscle soreness, lactate dehydrogenase level, creatine kinase activity, and oxidative damage (xylenol and protein carbonyl). Antioxidant enzymes (superoxide dismutase, catalase, and gluthatione peroxidase) and inflammatory markers (tumor necrosis factor, interleukin-1β (IL-1β), and interleukin-10 (IL-10)) were not altered during the recovery period compared with the placebo group. The results suggest that taurine supplementation represents an important factor in improving performance and decreasing muscle damage and oxidative stress but does not decrease the inflammatory response after EE.

Résumé

Cette étude se propose d’examiner les effets de la supplémentation en taurine sur la performance musculaire, le stress oxydatif et la réponse inflammatoire à la suite d’un exercice pliométrique chez des hommes. On répartit aléatoirement une sélection de 21 hommes (21 ± 6 ans, 78,2 ± 5 kg, 176 ± 7 cm) dans deux groupes : placebo (n = 10) et taurine (n = 11). Quatorze jours après le début de la supplémentation, les sujets effectuent sur un banc Scott trois séries d’exercices pliométriques des fléchisseurs du coude (80 % 1 RM) jusqu’à épuisement. On prélève des échantillons sanguins et on évalue la performance musculaire aux jours 1, 14, 16, 18 et 21 suivant le début de la supplémentation. Puis on analyse la performance, les lésions musculaires, le stress oxydatif et les marqueurs de l’inflammation. La supplémentation en taurine suscite une augmentation de la force et du contenu total en thiol ainsi qu’une diminution de la douleur musculaire, de la concentration de lactate déshydrogénase, de l’activité de la créatine kinase et des lésions oxydatives (xylénol et protéine carbonylée). Pendant la période de récupération, on n’observe dans les groupes supplémentés aucune modification de l’activité des enzymes antioxydantes (superoxyde dismutase, catalase et glutathion peroxydase) et des marqueurs de l’inflammation (facteur de nécrose tumorale, interleukine-1β (IL-1β) et interleukine-10 (IL-10)) comparativement au groupe placebo. D’après ces observations, la supplémentation en taurine constitue un moyen important pour améliorer la performance et diminuer les lésions musculaires et le stress oxydatif, mais elle ne diminue pas la réponse inflammatoire consécutive à un exercice pliométrique. [Traduit par la Rédaction]

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Published In

cover image Applied Physiology, Nutrition, and Metabolism
Applied Physiology, Nutrition, and Metabolism
Volume 39Number 1January 2014
Pages: 101 - 104

History

Received: 19 June 2012
Accepted: 25 March 2013
Accepted manuscript online: 25 June 2013
Version of record online: 25 June 2013

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Key Words

  1. taurine
  2. eccentric exercise
  3. physical performance
  4. oxidative stress
  5. inflammation
  6. supplementation

Mots-clés

  1. taurine
  2. exercice pliométrique
  3. performance physique
  4. stress oxydatif
  5. inflammation
  6. supplementation

Authors

Affiliations

Luciano A. da Silva
Exercise Biochemistry and Physiology Laboratory, Postgraduate Program in Health Sciences, Health Sciences Unit, Universidade do Extremo Sul Catarinense, 88806-000, Criciúma, SC, Brazil.
Fundação Educacional Barriga Verde, Curso de Educação Física, Orleans, SC, Brazil.
Camila B. Tromm
Exercise Biochemistry and Physiology Laboratory, Postgraduate Program in Health Sciences, Health Sciences Unit, Universidade do Extremo Sul Catarinense, 88806-000, Criciúma, SC, Brazil.
Karoline F. Bom
Exercise Biochemistry and Physiology Laboratory, Postgraduate Program in Health Sciences, Health Sciences Unit, Universidade do Extremo Sul Catarinense, 88806-000, Criciúma, SC, Brazil.
Izadora Mariano
Exercise Biochemistry and Physiology Laboratory, Postgraduate Program in Health Sciences, Health Sciences Unit, Universidade do Extremo Sul Catarinense, 88806-000, Criciúma, SC, Brazil.
Bruna Pozzi
Exercise Biochemistry and Physiology Laboratory, Postgraduate Program in Health Sciences, Health Sciences Unit, Universidade do Extremo Sul Catarinense, 88806-000, Criciúma, SC, Brazil.
Guilherme L. da Rosa
Exercise Biochemistry and Physiology Laboratory, Postgraduate Program in Health Sciences, Health Sciences Unit, Universidade do Extremo Sul Catarinense, 88806-000, Criciúma, SC, Brazil.
Talita Tuon
Exercise Biochemistry and Physiology Laboratory, Postgraduate Program in Health Sciences, Health Sciences Unit, Universidade do Extremo Sul Catarinense, 88806-000, Criciúma, SC, Brazil.
Gabrielle da Luz
Exercise Biochemistry and Physiology Laboratory, Postgraduate Program in Health Sciences, Health Sciences Unit, Universidade do Extremo Sul Catarinense, 88806-000, Criciúma, SC, Brazil.
Francilele Vuolo
Experimental Pathophysiology Laboratory, UNESC, Brazil.
Fabricia Petronilho
Experimental Pathophysiology Laboratory, UNESC, Brazil.
Willians Cassiano
Exercise Biochemistry and Physiology Laboratory, Postgraduate Program in Health Sciences, Health Sciences Unit, Universidade do Extremo Sul Catarinense, 88806-000, Criciúma, SC, Brazil.
Claudio T. De Souza
Exercise Biochemistry and Physiology Laboratory, Postgraduate Program in Health Sciences, Health Sciences Unit, Universidade do Extremo Sul Catarinense, 88806-000, Criciúma, SC, Brazil.
Ricardo Aurino Pinho
Exercise Biochemistry and Physiology Laboratory, Postgraduate Program in Health Sciences, Health Sciences Unit, Universidade do Extremo Sul Catarinense, 88806-000, Criciúma, SC, Brazil.

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