The effects of a 6-month resistance training and dried plum consumption intervention on strength, body composition, blood markers of bone turnover, and inflammation in breast cancer survivors
Publication: Applied Physiology, Nutrition, and Metabolism
23 September 2013
Abstract
The purpose of this study was to examine the effects of resistance training (RT) and dried plum (DP) consumption on strength, body composition, blood markers of bone, and inflammation in breast cancer survivors (BCS). Twenty-three BCS (RT, n = 12; RT+DP, n = 11), aged 64 ± 7 years, were evaluated at baseline and after 6 months of intervention on the following: muscular strength (chest press and leg extension) via 1-repetition maximums (1RMs); body composition, specifically bone mineral density (BMD) by dual energy X-ray absorptiometry; biochemical markers of bone turnover (bone-specific alkaline phosphatase (BAP), tartrate resistant acid phosphatase (TRAP-5b)); and inflammation (C-reactive protein (CRP)). Target RT prescription was 2 days/week of 10 exercises, including 2 sets of 8–12 repetitions at ∼60%–80% of 1RM. RT+DP also consumed 90 g of DP daily. There were no baseline differences between groups or any group-by-time interactions for any of the variables. BCS increased upper (p < 0.05) (RT: 64 ± 14 to 80 ± 17 kg; RT+DP: 72 ± 23 to 91 ± 20 kg) and lower (p < 0.05) (RT: 69 ± 20 to 87 ± 28 kg; RT+DP: 78 ± 19 to 100 ± 21 kg) body strength. Body composition and BMD improvements were not observed. TRAP-5b decreased in the RT group (p < 0.05) (4.55 ± 1.57 to 4.04 ± 1.63 U/L) and the RT+DP group (p = 0.07) (5.10 ± 2.75 to 4.27 ± 2.03 U/L). Changes in BAP and CRP were not observed. RT was effective for improving biochemical markers of bone turnover and muscular strength in BCS. A longer and higher intensity intervention may be needed to reveal the true effects of RT and DP on body composition and biochemical markers of inflammation.
Résumé
Cette étude se propose d’examiner les effets de l’entraînement contre résistance (« RT ») et de la consommation de pruneaux (« DP ») sur la force musculaire, la composition corporelle, les marqueurs sanguins du tissu osseux et l’inflammation chez les survivants du cancer du sein (« BCS »). Vingt-trois BCS (RT, n = 12; RT+DP, n = 11) âgées de 64 ± 7 ans participent à une évaluation des variables suivantes au début et après le programme d’intervention d’une durée de 6 mois : force musculaire (« 1RM », développé pectoral et extension des jambes), composition corporelle et plus spécifiquement la densité minérale osseuse (« BMD ») par absorptiométrie à rayons X en double énergie, marqueurs biochimiques du renouvellement du tissu osseux (phosphatase alcaline spécifique aux os (« BAP »), phosphatase acide résistant aux tartrates (« TRAP-5b »)) et l’inflammation (protéine C-réactive (« CRP »)). Le programme RT consiste principalement en 10 exercices comprenant deux séries de 8–12 répétitions à ∼60–80 % 1RM, et ce, à raison de 2 fois par semaine. Le groupe RT+DP consomme en plus 90 g de DP tous les jours. Toutes les variables ne présentent ni différences entre les groupes au début du programme, ni d’interaction groupe-temps. On observe chez les BCS une augmentation de la force du haut du corps (p < 0,05) (RT : de 64 ± 14 à 80 ± 17 kg; RT+DP : de 72 ± 23 à 91 ± 20 kg) et du bas du corps (p < 0,05) (RT : de 69 ± 20 à 87 ± 28 kg; RT+DP : de 78 ± 19 à 100 ± 21 kg). On n’observe aucune amélioration de la composition corporelle et de la BMD. On observe une diminution de TRAP-5b dans le groupe RT (p < 0,05) (de 4,55 ± 1,57 à 4,04 ± 1,63 U/L) et dans le groupe RT+DP (p = 0,07) (de 5,10 ± 2,75 à 4,27 ± 2,03 U/L). On n’observe aussi aucune modification de BAP et de CRP. Le programme RT est efficace pour améliorer les marqueurs biochimiques du renouvellement du tissu osseux et la force musculaire chez les BCS. Il faut peut-être prolonger et intensifier le programme d’intervention pour révéler les effets réels de RT et de DP sur la composition corporelle et les marqueurs biochimiques de l’inflammation. [Traduit par la Rédaction]
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Published In
Applied Physiology, Nutrition, and Metabolism
Volume 39 • Number 6 • June 2014
Pages: 730 - 739
History
Received: 25 June 2013
Accepted: 4 September 2013
Accepted manuscript online: 23 September 2013
Version of record online: 23 September 2013
Notes
This paper is a part of a Special Issue entitled The role of diet, body composition, and physical activity on cancer prevention, treatment, and survivorship.
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© 2013.
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SimonaviceEmily, LiuPei-Yang, IlichJasminka Z., KimJeong-Su, ArjmandiBahram, and PantonLynn B.. 2014. The effects of a 6-month resistance training and dried plum consumption intervention on strength, body composition, blood markers of bone turnover, and inflammation in breast cancer survivors. Applied Physiology, Nutrition, and Metabolism.
39(6): 730-739. https://doi.org/10.1139/apnm-2013-0281
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