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BIOSYNTHESIS OF BERBERINE AND BERBERASTINE INCORPORATION OF CATECHOLAMINES

Publication: Canadian Journal of Chemistry
July 1965

Abstract

Dopamine serves as a precursor of berberastine, berberine, hydrastine, and canadine in Hydrastis canadensis L. Noradrenaline serves as a precursor of berberastine but is not incorporated into the other three bases. It is shown that the incorporation of labelled dopamine into berberine and of labelled noradrenaline into berberastine takes place without randomization of radioactivity.

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cover image Canadian Journal of Chemistry
Canadian Journal of Chemistry
Volume 43Number 7July 1965
Pages: 2017 - 2026

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Version of record online: 3 February 2011

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Cited by

1. Berberine: A Comprehensive Review on its Isolation, Biosynthesis, Chemistry and Pharmacology
2. Hendersine A, a novel isoquinoline alkaloid from Corydalis hendersonii
3. Prevention of peroxidation of cardiolipin liposomes by quinol-based antioxidants
4. Chapter 2 β-Phenethylamines and Ephedrines of Plant Origin
5. Isoquinoline Alkaloids
6. Biosynthesis of Isoquinolines
7. Alkaloids Derived from Phenylalanine and Tyrosine
8. Syntheses and stereochemistry of 4-hydroxy tetrahydroisoquinolines in the 1-benzyl and 1-phenethyl series. Efficient routes to isopavines and homoisopavines
9. The synthesis of berberastine
10. Alteration of norepinephrine metabolism by barbiturates
11. 1,2-Dihydroisoquinolines
12. The synthesis of isopavine alkaloids—I
13. Isopavine alkaloids: Synthesis biosynthetic speculations
14. Isoquinoline Alkaloids
15. Chapter 6 The Benzylisoquinoline Alkaloids
16. Chapter 2 The Protoberberine Alkaloids
17. Thalictrum alkaloids II. Thalidastine
18. ALKALOID BIOGENESIS

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